| ORIGINAL CONTRIBUTION: NOVEL APPROACHES IN TROPICAL MEDICINE |
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| Year : 2015 | Volume
: 2
| Issue : 2 | Page : 69-71 |
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Devising a prognostic predictive scale based on lactate dehydrogenase levels in dengue
Saumya H Mittal1, Salony Mittal2, Tuhina Govil3
1 Department of Medicine, Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India
2 Department of Pathology, KMC University, Mangalore, Karnataka, India
3 Detroit Medical Centre, Children's Hospital of Michigan, Detroit, USA
Correspondence Address:
Saumya H Mittal
Department of Medicine, Apollo Hospital, Delhi
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2349-0977.172679
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Aims and Objectives: To find a predictive scale for the duration of stay in the hospital in patients of dengue with no previous comorbidities, at a tertiary care centre. Materials and Methods: All patients consenting to be a part of the treatment were subjected to a detailed history and physical examination. The diagnosis of dengue was confirmed by either Dengue NS1 antigen or IgM Dengue serology (ELISA). Thereafter, their general condition and investigations such as the platelet counts were closely monitored. Lactate dehydrogenase (LDH) levels were done on the day of minimum platelet counts. The duration of symptom onset, date of admission, and duration of hospital stay were recorded. They were discharged when their platelet count showed significant increase in three consecutive samples. Results: On statistical analyses, the mean number of days to discharge from the date of testing LDH was 2.43 ± 1.10 days (P = 0.0001, r = 0.8178). The mean number of days to discharge calculated by LDH in dengue (LID) scale was 2.43 ± 1.04 days and the mean number of days to actual discharge from the date of testing LDH was 2.43 ± 1.10 days (P = 1).Conclusion: A possible date of discharge could be determined accurately by the levels of LDH tested at the time of the lowest platelet count. Using this LID scale, discharge date can be predicted. |
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