| PRACTICE CHANGING CONTINUING EDUCATION - CLINICS IN ENDOCRINE HISTOPATHOLOGY |
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| Year : 2018 | Volume
: 4
| Issue : 4 | Page : 240-250 |
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Pituitary tumors: Changing paradigms in understanding, nomenclature and the newer basis of classification
Sadhana Tiwari, Ishita Pant, Sujata Chaturvedi
Department of Pathology, Institute of Human Behaviour and Allied Sciences, Delhi, India
Correspondence Address:
Sujata Chaturvedi
Department of Pathology, Institute of Human Behaviour and Allied Sciences, Dilshad Garden, Delhi - 110 095
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/astrocyte.astrocyte_43_18
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The pituitary gland is embryologically divided into two main lobes: adenohypophysis (anterior) and neurohypophysis (posterior). Last five decades have witnessed changes in the tumor classifications – anterior pituitary in 2017 and posterior in 2016, based on hormonal immunohistochemistry, molecular profiles, and pituitary specific transcription factors. Few newer entities/terms have been added and at the same time certain terms have been modified/discarded. In this article, relevant anatomy, development, histology, incidence, and clinical manifestations of pituitary tumors evolution of various classification systems and recommended current classification of pituitary tumors; the genetic alterations and the diagnostic implications for today's pathologist have been reviewed in a comprehensive manner.
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